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MCAO sutures Diameter 0.29mm

MCAO sutures in this category of coated tip diameter 0.29 mm are suitable for MCAO models in animals within body weight range 140 +/- 15 grams.

Coating lengths are available from 1-2 mm to 9-10 mm. A super long coating length from 10 mm to 15 mm may also be possible through special request to Doccol. The most commonly purchased MCAO sutures have coating lengths of 5-6 mm and 4-5 mm. A shorter coating length leaves more bare surface area on the MCAO suture, which makes the surgeon feel easier to handle it. However, a shorter coating length may increase the chance of incomplete occlusion in inexperienced hands. If the coated part of the MCAO suture passes over the origin of MCA, the blood from the posterior circulation may reach MCA through the residue space around the uncoated part of the MCAO suture. A longer coating length may increase the chance of complete occlusion; however, its increased contacting area with endothelial cells may cause more traction force on those contacted endothelial cells. Such traction may cause endothelial cell damage when you withdraw the MCAO suture for reperfusion. In a summary, a shorter length may be good for reperfusion while longer length good for permanent occlusion; and the selection of the coating length will depend on your own study design, lab setting, and your surgical skill.

Regular monofilaments are designed for just one time use for most common experiments, and are not recommended for repeated use. Reusable MCAO sutures are specially designed and manufactured such that they have a more uniformed coating surface and a more rigid bare filament, which make them maintaining their shapes better after their initial use than the disposable ones do. They are designed to use twice and may be ideal for the in vivo efficacy study by using paired-controls, in which the paired animals have the same body weight and use the same monofilament. Such a use of paired-controls may drastically increase the consistence of infarction volume. In a catalog number “Re” stands for reusable.

Displaying 1 to 12 (of 12 products) Result Pages:  1 
    Item #   Product Name+   Price   Buy Now 
 5-0 fine MCAO suture L12 PK10   502912PK10   5-0 fine MCAO suture L12 PK10   Please log in to see prices 
 5-0 fine MCAO suture L12 PK5Re   502912PK5Re   5-0 fine MCAO suture L12 PK5Re   Please log in to see prices 
 5-0 fine MCAO suture L23 PK10   502923PK10   5-0 fine MCAO suture L23 PK10   Please log in to see prices 
 5-0 fine MCAO suture L23 PK5Re   502923PK5Re   5-0 fine MCAO suture L23 PK5Re   Please log in to see prices 
 5-0 fine MCAO suture L34 PK10   502934PK10   5-0 fine MCAO suture L34 PK10   Please log in to see prices 
 5-0 fine MCAO suture L34 PK5Re   502934PK5Re   5-0 fine MCAO suture L34 PK5Re   Please log in to see prices 
 5-0 fine MCAO suture L45 PK10   502945PK10   5-0 fine MCAO suture L45 PK10   Please log in to see prices 
 5-0 fine MCAO suture L45 PK5Re   502945PK5Re   5-0 fine MCAO suture L45 PK5Re   Please log in to see prices 
 5-0 fine MCAO suture L56 PK10   502956PK10   5-0 fine MCAO suture L56 PK10   Please log in to see prices 
 5-0 fine MCAO suture L56 PK5Re   502956PK5Re   5-0 fine MCAO suture L56 PK5Re   Please log in to see prices 
 5-0 fine MCAO suture L910 PK10   5029910PK10   5-0 fine MCAO suture L910 PK10   Please log in to see prices 
 5-0 fine MCAO suture L910 PK5Re   5029910PK5Re   5-0 fine MCAO suture L910 PK5Re   Please log in to see prices 
Displaying 1 to 12 (of 12 products) Result Pages:  1 

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