Doccol provides MCAO (middle cerebral artery occlusion) sutures for inducing ischemic stroke models in rats and mice since 2004, Doccol products are referred by thousands of scholarly articles. Doccol MCAO sutures are silicone-rubber coated nylon monofilaments, in which the silicone-rubber coating is engineered for ensuring a complete occlusion of the middle cerebral artery (MCA) origin while avoiding subarachnoid hemorrhage (SAH). Using Doccol MCAO sutures for inducing stroke models has been widely accepted as a necessary technical step, and it is also a new standard for ensuring the highest quality of stroke modeling. Using Doccol MCAO sutures for inducing stroke models has been reported to be able to drastically decrease the within-group variation of stroke models, reducing the standard deviation (SD) to 5% of the mean value for infarction volume. For more information please read Doccol Made a Difference in Stroke Modeling.
MCAO sutures are available in nylon monofilament material USP size 3-0, 4-0, 5-0, 6-0, 7-0, and 8-0, which are categorized first by coating diameter, then further by coating length. We provide a match chart below to help you select coating diameters:
|
Animal Body
Weight (g)
|
Suggested
tip Diameters (mm)
|
Bare filament
USP “0”
|
|
12-15
|
0.15, 0.17
|
8-0, 7-0
|
|
15-20
|
0.17, 0.19
|
8-0, 7-0
|
|
21-25
|
0.21, 0.22
|
8-0, 7-0, 6-0
|
|
26-30
|
0.22, 0.23
|
8-0, 7-0, 6-0
|
|
31-35
|
0.23, 0.24
|
8-0, 7-0, 6-0
|
|
36-200
|
0.24 - 0.33
|
5-0, 6-0
|
|
201-250
|
0.33, 0.35
|
5-0, 4-0
|
|
251-280
|
0.35, 0.37
|
5-0, 4-0
|
|
281-330
|
0.37, 0.39
|
5-0, 4-0
|
|
331-400
|
0.41
|
4-0, 3-0
|
|
401-500
|
0.43, 0.45
|
4-0, 3-0
|
|
501-600
|
0.47, 0.49
|
4-0, 3-0
|
|
601-700
|
0.51, 0.54
|
3-0
|
|
701-800
|
0.54
|
3-0
|
|
801-900
|
0.54, 0.58
|
3-0
|
|
901-1000
|
0.58
|
3-0
|
Doccol provides MCAO sutures for the following tip (coated part) diameters: |
