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We are referred by over a thousand scholarly articles | Customers who use Doccol products

MCAO Sutures - Doccol solution - referred by over a thousand articles

MCAO Sutures

Doccol provides MCAO (middle cerebral artery occlusion) sutures for inducing ischemic stroke models in rats and mice since 2004, Doccol products are referred by over a thousand scholarly articles. MCAO sutures are silicone-rubber coated nylon monofilaments, in which the silicone-rubber coating is engineered for ensuring a complete occlusion of the middle cerebral artery (MCA) origin while avoiding subarachnoid hemorrhage (SAH). Using Doccol MCAO sutures for inducing stroke models has been widely accepted as a necessary technical step, and it is also a new standard for ensuring the highest quality of stroke modeling.  Using Doccol MCAO sutures for inducing stroke models has been reported to be able to drastically decrease the within-group variation of stroke models, reducing the standard deviation (SD) to 5% of the mean value for infarction volume. For more information please read Doccol Made a Difference in Stroke Modeling.

MCAO sutures are available in nylon monofilament material USP size 3-0, 4-0, 5-0, 6-0, 7-0, and 8-0, which are categorized first by coating diameter, then further by coating length. We provide a match chart below to help you select coating diameters:

 

Animal Body
Weight (g)

Suggested
tip Diameters (mm)

Bare filament
USP “0”

12-15

0.15, 0.17

8-0, 7-0

15-20

0.17, 0.19

8-0, 7-0

21-25

0.21, 0.22

8-0, 7-0, 6-0

26-30

0.22, 0.23

8-0, 7-0, 6-0

31-35

0.23, 0.24

8-0, 7-0, 6-0

36-200

0.24 - 0.33

5-0, 6-0

201-250

0.33, 0.35

5-0, 4-0

251-280

0.35, 0.37

5-0, 4-0

281-330

0.37, 0.39

5-0, 4-0

331-400

0.41

4-0, 3-0

401-500

0.43, 0.45

4-0, 3-0

501-600

0.47, 0.49

4-0, 3-0

601-700

0.51, 0.54

3-0

701-800

0.54

3-0

801-900

0.54, 0.58

3-0

901-1000

0.58

3-0

Doccol provides MCAO sutures for the following tip (coated part) diameters:


Diameter 0.15mm

Diameter 0.17mm

Diameter 0.18mm

Diameter 0.19mm

Diameter 0.20mm

Diameter 0.21mm

Diameter 0.22mm

Diameter 0.23mm

Diameter 0.24mm

Diameter 0.25mm

Diameter 0.26mm

Diameter 0.27mm

Diameter 0.29mm

Diameter 0.31mm

Diameter 0.33mm

Diameter 0.35mm

Diameter 0.36mm

Diameter 0.37mm

Diameter 0.38mm

Diameter 0.39mm

Diameter 0.41mm

Diameter 0.43mm

Diameter 0.45mm

Diameter 0.47mm

Diameter 0.49mm

Diameter 0.51mm

Diameter 0.54mm

Diameter 0.58mm

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