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Medium MCAO suture 40L34R10
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MCAO sutures Diameter 0.20mm

Manufacturer: Doccol

MCAO sutures in this category of coated tip diameter 0.20 mm are suitable for MCAO models in animals within body weight range 20 +/- 2 grams.

Coating lengths are available from 1-2 mm to 9-10 mm. A super long coating length from 10 mm to 15 mm may also be possible through special request to Doccol. The most commonly purchased MCAO sutures have coating lengths of 5-6 mm and 4-5 mm. A shorter coating length leaves more bare surface area on the MCAO suture, which makes the surgeon feel easier to handle it. However, a shorter coating length may increase the chance of incomplete occlusion in inexperienced hands. If the coated part of the MCAO suture passes over the origin of MCA, the blood from the posterior circulation may reach MCA through the residue space around the uncoated part of the MCAO suture. A longer coating length may increase the chance of complete occlusion; however, its increased contacting area with endothelial cells may cause more traction force on those contacted endothelial cells. Such traction may cause endothelial cell damage when you withdraw the MCAO suture for reperfusion. In a summary, a shorter length may be good for reperfusion while longer length good for permanent occlusion; and the selection of the coating length will depend on your own study design, lab setting, and your surgical skill.

Regular monofilaments are designed for just one time use for most common experiments, and are not recommended for repeated use. Reusable MCAO sutures are specially designed and manufactured such that they have a more uniformed coating surface and a more rigid bare filament, which make them maintaining their shapes better after their initial use than the disposable ones do. They are designed to use twice and may be ideal for the in vivo efficacy study by using paired-controls, in which the paired animals have the same body weight and use the same monofilament. Such a use of paired-controls may drastically increase the consistence of infarction volume. In a catalog number “Re” stands for reusable.

Displaying 1 to 18 (of 18 products) Result Pages:  1 
    Item #   Product Name+   Price   Buy Now 
 Medium MCAO suture 70L12   702012PK5Re   Medium MCAO suture 70L12   Please log in to see prices 
 Medium MCAO suture 70L23   702023PK5Re   Medium MCAO suture 70L23   Please log in to see prices 
 Medium MCAO suture 70L34   702034PK5Re   Medium MCAO suture 70L34   Please log in to see prices 
 Medium MCAO suture 70L45   702045PK5Re   Medium MCAO suture 70L45   Please log in to see prices 
 Medium MCAO suture 70L56   702056PK5Re   Medium MCAO suture 70L56   Please log in to see prices 
 Medium MCAO suture 70L56C   702056PK5   Medium MCAO suture 70L56C   Please log in to see prices 
 Medium MCAO suture 70L910   7020910PK5Re   Medium MCAO suture 70L910   Please log in to see prices 
 Medium MCAO suture 80L12   802012PK5   Medium MCAO suture 80L12   Please log in to see prices 
 Medium MCAO suture 80L23   802023PK5   Medium MCAO suture 80L23   Please log in to see prices 
 Medium MCAO suture 80L34   802034PK5   Medium MCAO suture 80L34   Please log in to see prices 
 Medium MCAO suture 80L45   802045PK5   Medium MCAO suture 80L45   Please log in to see prices 
 Medium MCAO suture 80L56   802056PK5   Medium MCAO suture 80L56   Please log in to see prices 
 Superfine MCAO suture 60L12C   602012PK10   Superfine MCAO suture 60L12C   Please log in to see prices 
 Superfine MCAO suture 60L23C   602023PK10   Superfine MCAO suture 60L23C   Please log in to see prices 
 Superfine MCAO suture 60L34C   602034PK10   Superfine MCAO suture 60L34C   Please log in to see prices 
 Superfine MCAO suture 60L45C   602045PK10   Superfine MCAO suture 60L45C   Please log in to see prices 
 Superfine MCAO suture 60L56C   602056PK10   Superfine MCAO suture 60L56C   Please log in to see prices 
 Superfine MCAO suture 60L56R   602056PK10Re   Superfine MCAO suture 60L56R   Please log in to see prices 
Displaying 1 to 18 (of 18 products) Result Pages:  1 
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