Introducing our Fine MCAO suture (Silicone Rubber-Coated Monofilament) - a precision-crafted microsurgical tool for inducing Middle Cerebral Artery Occlusion (MCAO) stroke model in mice. Crafted with meticulous attention to detail, this 80L12 subtype is instrumental for skilled surgeons working on younger mice, delivering consistent and reliable results for your experiments. Each pack contains 5 monofilaments.

Key Features:

1. Filament Specifications: The 8-0 filament size has a diameter ranging from 0.04 to 0.05 mm and a length of 20 mm, providing the needed flexibility for working on vulnerable vasculature. It minimizes the stretch on Willis Circle.

2. Silicone Rubber Coating: With a diameter of 0.19 +/- 0.01 mm, the silicone rubber coating ensures smooth and controlled insertion, enhancing precision in your experiments. Such coating provides ideal dimensions for MCAO procedures in mice within the body weight range of 18 +/- 2 grams. The coating extends 1-2 mm, catering to the extended needs of skilled surgeons engaged in longer (>60 min) MCAO period followed by reperfusion.

3. Suitable for Skilled Surgeons: Tailored for experienced practitioners, our filament is specifically designed to meet the demands of skilled surgeons undertaking state of art MCAO surgeries. The desired coating length provides the control for intricate procedures, ensuring procise MCA occlusion but keep open the posterior communicating arteries which are vital for the hypothalamus. For these reasons, it is able to reduce the chance of sustained post-surgery high fever which causes high mortality in MCAO stroke models.