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Microcatheters for Rats/Mice
Microcatheters for Rats/Mice

Doccol micro catheters were specially designed for improving the performance, quality and productivity in rodent blood sampling, drug delivery, small flow rate liquid transferring, and physiological monitoring, in which invasive vascular access is necessary. Doccol provides sufficient choices of micro catheters for vascular cannulation in all common locations, such as the tail, femoral, carotid, and brachial veins and arteries, and also the jugular veins. The following features make Doccol microcatheters superior to its competitors:

  • Doccol knows the frustration and pain in making and using “home-made” microcatheters, our microcatheters are permanently connected to an industrial standard Luer lock or stopcock, therefore, eliminated the transitional tubing and needle connection. Doccol microcatheters offer the convenience of direct use with in dustrial standard syringes with Luer fitting.
  • Dramatically reduced inner volume allows minimal disturbance of local blood flow dynamics.
  • Although the microcatheters are extremely fine, they offer excellent pushability; tubing OD covering a range from 0.081 mm to 0.838 mm with sufficient choices; these features make them suitable for the access of deep microvascularure.
  • Microcatheter tubings are available in several materials, such as polyimide, teflon, polyethylene, vinyl, and polyurethane.
  • These microcatheters are durable and can be repeatedly used.

References:

Arnberg F, Lundberg J, Kenne E, et al. Superselective intra-arterial umbilical cord blood administration to BM in experimental animals. Bone Marrow Transplantation. 2014;49(12):1486-1491. doi:10.1038/bmt.2014.190.

Namestnikova, D & Gubskiy, Il'ya & Gabashvili, A & Sukhinich, Kirill & Melnikov, Pavel & Vishnevskiy, D & Soloveva, A & Vitushev, E & Chekhonin, V & Gubsky, Leonid & Yarygin, Konstantin. (2017). MRI evaluation of frequent complications after intra-arterial transplantation of mesenchymal stem cells in rats. Journal of Physics: Conference Series. 886. 012012. 10.1088/1742-6596/886/1/012012.

Namestnikova D, Gubskiy I, Kholodenko I, Melnikov P, Sukhinich K, et al. (2017) Methodological aspects of MRI of transplanted superparamagnetic iron oxide-labeled mesenchymal stem cells in live rat brain. PLOS ONE 12(10): e0186717. https://doi.org/10.1371/journal.pone.0186717

To select a microcatheter, you will need to know the size of vessel that you are going to catheterize. The principal is that the outer diameter of a microcatheter should be smaller than the vessel inner diameter. You may use the following chart as a guidance in determing the tubing O.D. of your microcatheter according to the animal body weight. Tubing length can be customized.

 

Maximum microcatheter O.D. (mm) for artery cannulation
Body Weight (g) Femoral  Tail
(upper 2/3)
Carotid
(lower 2/3)
Brachial
<15 0.136 0.136 0.327 0.127
15-20 0.159 0.159 0.382 0.127
20-25 0.205 0.205 0.491 0.164
25-30 0.250 0.250 0.600 0.200
30-35 0.275 0.295 0.660 0.220
<200 0.328 0.328 0.590 0.262
<200-250 0.369 0.369 0.664 0.295
250-280 0.434 0.434 0.782 0.348
280-330 0.500 0.500 0.900 0.400
330-400 0.598 0.598 1.077 0.479
>400 0.656 0.656 1.180 0.525

 

Doccol provides microcatheters for the following diameters:


OD .01-0.1 mm

OD 0.1-0.2 mm

OD 0.2-0.3 mm

OD 0.3-0.4 mm

OD 0.5-0.6 mm

OD 0.6-0.7 mm

OD 0.7-0.8 mm

OD 0.8-0.9 mm

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